[FieldTrip] Source statistics on trial-based MEG data (MNE)

Nora Holtz holtznor at hu-berlin.de
Tue Apr 19 10:50:34 CEST 2022

Hi Jan Mathijs, 

Thanks for your reply! I would like to adopt a two-step approach. First, on a subject-level I want to run a correlation analysis between neural activity and RT for each subject (i.e., across trials). As a result I obtain a matrix of Rho values for each subject which I then want to  enter into a group level cluster-based permutation test. We have already adopted this approach on the sensor level - but with source level data we are not sure how to do it. For example how do we compute neighbours (when using MNE approach)? I’d be grateful for any help.



> On 13 Apr 2022, at 15:03, Schoffelen, J.M. (Jan Mathijs) via fieldtrip <fieldtrip at science.ru.nl> wrote:
> Hi Nora,
> How would you compute a correlation between reaction time (in a trial) and the source activity for that trial? I guess you want to compute the correlation across trials?
> Best,
> JM
>> On 13 Apr 2022, at 14:34, Nora Holtz via fieldtrip <fieldtrip at science.ru.nl <mailto:fieldtrip at science.ru.nl>> wrote:
>> Hi all, 
>> I am currently doing source localisation of my MEG data with the MNE method. Now I want to correlate the source activity (sources x time) for each trial (1705 trials) with behavioural reaction time in this trial. 
>> Afterwards, I want to do a cluster based permutation test on these correlations (averaged over trials). 
>> I do not have individual MRI data, so I am working with templates. 
>> To my knowledge, ft_sourcestatistics does not work on MNE source x time data, right? Does anyone have suggestions on how to proceed here?
>> Thanks in advance!!
>> Nora
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