[FieldTrip] Possible to combine FEM model with surface-based model of dipole locations?

[Carsten Wolters]

Dear George,

for the FEM:
 From Johannes (in CC) FieldTrip-SimBio paper
https://biomedical-engineering-online.biomedcentral.com/articles/10.1186/s12938-018-0463-y
it doesn't get clear if a cortical surface source space or a volumetric 
one was used for the dipole scan, I only found
"In the call of /ft_prepare_sourcemodel/, a grid resolution of 2 mm was 
chosen for the source space."

In general, if you distinguish inner compartments such as white and grey 
matter and CSF, I would recommend
to combine it with a cortical surface source space, as done in most of 
our papers, see e.g. Section 2.5 in
http://www.sci.utah.edu/~wolters/PaperWolters/2014/VorwerkChoRamppHamerKnoescheWolters_NeuroImage_2014_Webversion.pdf

BR
    Carsten

-- 
Prof. Dr.rer.nat. Carsten H. Wolters
University of Münster
Institute for Biomagnetism and Biosignalanalysis
Malmedyweg 15
48149 Münster, Germany

Phone:
+49 (0)251 83 56904
+49 (0)251 83 56865 (secr.)

Fax:
+49 (0)251 83 56874

Email: carsten.wolters at uni-muenster.de
Web: https://campus.uni-muenster.de/biomag/das-institut/mitarbeiter/carsten-wolters/



Am 03.05.21 um 14:21 schrieb George Buzzell:
>
> Dear FSL Community,
>
> For source localization analyses (using individual MRIs), is there an 
> established workflow/approach in fieldtrip to model all aspects of the 
> inside of the head as volumetric (i.e. employ a FEM model) but 
> restrict the source model (dipole locations) to a surface-based model 
> of the gray matter (i.e. using fieldtrip)?
>
> My understanding is that there are two typical workflows for 
> conducting source localization:
>
>  1. Use of a FEM (volumetric) head model with a volumetric source grid
>     model
>  2. Use of a BEM (boundary/surface) head model with a surface-based
>     source model (created via free-surfer).
>
> I have traditionally employed approach #1 above. However, I am 
> wondering if it is possible to combine a FEM (volumetric) head model 
> with surface-based modelling of the gray matter (and dipole 
> locations). My reasoning for wanting to do this is that I would 
> presume that FEM allows for improved modelling of the way electricity 
> flows through the internal media of the head, but, a surface model for 
> dipole locations would lead to more accurate modeling of their 
> locations and orientations.
>
> I would be grateful for any comments, insights, links to resources 
> and/or example code. Also, if something is off in the way I am 
> thinking about this, please do let me know!
>
> Best,
>
> George
>
> -- 
>
> George A. Buzzell
>
> Assistant Professor
>
> Florida International University
>
> Lab website: www.NDCLab.com <http://www.NDCLab.com>
>
>
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> https://doi.org/10.1371/journal.pcbi.1002202


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