[FieldTrip] Quality of beamforming on MNI template vs single-subject MRI

smoratti at psi.ucm.es smoratti at psi.ucm.es
Thu Apr 4 15:43:58 CEST 2013

Dear Andrea,

¿Did you normalize the volume of the individuals after source reconstruction and before doing statistics? If not, this might explain the difference.



Stephan Moratti, PhD

see also: http://web.me.com/smoratti/

Universidad Complutense de Madrid
Facultad de Psicología
Departamento de Psicología Básica I
Campus de Somosaguas
28223 Pozuelo de Alarcón (Madrid)


Center for Biomedical Technology
Laboratory for Cognitive and Computational Neuroscience
Parque Científico y Tecnológico de la Universidad Politecnica de Madrid
Campus Montegancedo
28223 Pozuelo de Alarcón (Madrid)

email: smoratti at psi.ucm.es
Tel.:    +34 679219982

El 04/04/2013, a las 14:18, Andrea Brovelli escribió:

> Dear all,
> I used DICS and compared the quality of the beamforming using two different source spaces (3D grids):
> 1) MNI template space as described in http://fieldtrip.fcdonders.nl/example/create_single-subject_grids_in_individual_head_space_that_are_all_aligned_in_mni_space
> 2) Single subject 3D grid using anatomical MRI
> The number of sources in the two models is similar (approx. 3500 sources). However, the results using the MNI template are less significant. That is, the statistical analysis testing a significant increase in power post-stimulus with respect to baseline give higher p-values (in some region of interest).
> Questions:
> Does anyone know why ?
> Is the use of the MNI template the only (and best) way to allow statistical analysis across subjects in the source space ?
> thanks a lot
> Andrea
> -- 
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