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Hi everyone, <br>
I was hoping someone could help me figure out where my source
analysis is going wrong. <br>
I have data on brain tumour patients (MRIs are from prior to tumour
resection). From the hospital (using CTF), I receive .mri files that
already have fiducial points saved as far as I was told. I then
reslice and segment the .mri file, after reading it with ft_read_mri<br>
mri_reslice = ft_volumereslice(, mri);<br>
segmentedmri = ft_volumesegment(, mri_reslice);<br>
This seems to be working:<br>
<img src="cid:firstname.lastname@example.org" alt="" height="268"
Plotting headmodel and sensors, it looks like they are aligned:<br>
<img src="cid:email@example.com" alt="" height="135"
If I compute the source model with MNI-warping (non-linear
transformation), I get something that doesn't seem right. I don't
know if this is because these are not normal brains to start with:<br>
<img src="cid:firstname.lastname@example.org" alt="" height="172"
With linear transformation, things look better:<br>
<img src="cid:email@example.com" alt="" height="188"
One of my questions is what the consequences are of using linear
transformation for the MNI warping given the pathological nature of
Then, the next issue is this result when projecting the source to
<img src="cid:firstname.lastname@example.org" alt="" height="172"
This happens regardless of whether I use the MNI-warped grid
interpolated to the MNI template, or the patient's individual grid
skipping the MNI normalisation step, interpolated to the patient's
But if I plot with 'ortho' method, then I see that the MNI-warped
and interpolated source data is misaligned, but the patient-native
space one isn't.<br>
<img src="cid:email@example.com" alt="" height="238"
I can't make sense of this anymore; I've been trying all kinds of
things that don't work, so I was wondering whether anyone has an
idea of what could be going on by looking at these figures. Is it an
error already at the level of alignment of the fiducials? Or is it
due to the MNI-warping? Or a combination of issues?<br>
Thanks very much for any kind of help!<br>