[FieldTrip] PSI correction and new perspective on clinical assessment and EEG validation

[נתי שטרן]

Dear FieldTrip community,

I am sharing a new perspective and proposed validation protocol for the
Psychiatric State Index (PSI), a proposed wearable EEG framework for
differentiating autistic meltdown from psychotic episode. It corrects the
clinical and measurement framing of my earlier PSI message:

Reframing the Psychiatric State Index Through Clinical Assessment and
Measurement Validation
Full manuscript with references:
https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.google.com%2Furl%3Fq%3Dhttps%3A%2F%2Fgithub.com%2Fnetanelcyber%2Fpsi-qeeg-bis%2Fblob%2F18e22b6dd4ddc8747b6c2034cc7f457ec1aff28f%2Fdocs%2Fresearch%2FPSI_CLINICAL_PERSPECTIVE.md%26source%3Dgmail%26ust%3D1792051043671000%26sa%3DE&data=05%7C02%7Cfieldtrip%40science.ru.nl%7C8652ebeee563493c05f008df29c8cb39%7C084578d9400d4a5aa7c7e76ca47af400%7C1%7C0%7C639275615266030353%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C80000%7C%7C%7C&sdata=ZMqP2JGo1nEtJ6l31YtmGG%2FBSTBrQn06UquNfHsGZ7M%3D&reserved=0

This is an unreviewed manuscript for discussion; psychiatric review has
been requested and remains pending. The present software supports offline
research analyses. Available datasets do not establish imminent meltdown or
psychosis prediction.

The proposed primary human analysis excludes scalp gamma and scalp
theta-gamma PAC. Any secondary interpretation would require synchronized
EMG/EOG/movement measurements and expert artifact review. Numerical QC,
notch filtering or a finite spectral estimate does not establish neural
origin; entropy and spectral edge measures also require scrutiny.
Intracranial LFP findings remain a separate measurement domain.

I would welcome methodological advice on practical synchronized artifact
measurements, prespecified raw-signal review, and reporting unavailable
data during active movement/distress in EEG workflows. The article also
separates full journal evidence from preprints and conference abstracts,
and clinical assessment from numerical benchmarks.

Code and documented corrections:
https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.google.com%2Furl%3Fq%3Dhttps%3A%2F%2Fgithub.com%2Fnetanelcyber%2Fpsi-qeeg-bis%2Fpull%2F3%26source%3Dgmail%26ust%3D1792051043671000%26sa%3DE&data=05%7C02%7Cfieldtrip%40science.ru.nl%7C8652ebeee563493c05f008df29c8cb39%7C084578d9400d4a5aa7c7e76ca47af400%7C1%7C0%7C639275615266303957%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C80000%7C%7C%7C&sdata=IJYKsCLfATpE1i9NMN0VKvWu2PSPKUkzH39C1NfTbeY%3D&reserved=0

Separately, if an earlier PSI message of mine from today reached this list,
please note that three author names in it were wrong. The correct
attributions are:
- Kakuszi et al. (2024), Psychiatry Research 339:116040 (the message said
"Kaur et al.")
- Neo et al. (2023), Translational Psychiatry 13:389 (the message said "Sun
et al.")
- Leicht et al. (2016), Schizophrenia Bulletin (the message said
"Grent-'t-Jong et al. (2015)")

Best regards,
Netanel Stern
nsh531 at gmail.com
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