[FieldTrip] dipole fitting for studing resting states

Irene Varela Leniz irene.varela at alumni.mondragon.edu
Thu May 30 11:36:21 CEST 2019


Dear Matti,

Thank you for your response. Your answer has been very helpful.

Best regards,

Irene

El jue., 30 may. 2019 a las 11:25, Matti Stenroos (<matti.stenroos at aalto.fi>)
escribió:

> Hello Irene,
>
> Dipole fitting is used, when one has prior knowledge that the data is
> supposed to arise from one (single-dipole) or a couple of (multi-dipole)
> focal source regions. In event-related analysis, one typically studies a
> phenomenon that is (assumed to be) time-locked to the stimulus and
> repeated (almost) identically stimulus-by-stimulus. Then, giving many
> stimuli and averaging the data, one can suppress other brain activity
> and bring up the studied phenomenon. If the phenomenon is supposed to
> arise from focal region(s), for example in the case of somatosensory
> evoked potentials, dipole fitting can perform excellently.
>
> If one has no such prior information / study setting, dipole fitting is
> not necessarily useful. In classical dipole fitting, one explains the
> measurement using the dipoles. A couple of dipoles often explain the
> data very well, but that does not mean that the result would make any
> sense. So, in resting-state data, one rather selects a method that a)
> explains the data using the whole brain space, or b) uses a spatial
> filtering approach that scans the source space without aiming to explain
> the measurement. Case a) would be minimum norm estimation and case b)
> for example beamforming.
>
> Cheers,
>   Matti
>
>
>
>
>
> On 29/05/2019 17.18, Irene Varela Leniz wrote:
> > Dear Fieldtripers,
> >
> > I am following the tutorial "Dipole fitting of combined MEG/EEG data".
> > Here, there is a sentence /"information about how to fit dipole models
> > to the event-related fields (MEG) and potentials (EEG) of a single
> > subject". /Does the author want to express with this that the approach
> > dipole fitting is  used with Event Related Potentials?
> >
> > I have been looking in literature and have only found studies based on
> > beamforming to study resting states. Does anyone know if the approach
> > dipole fitting can also be used in these cases? Or is it more convenient
> > to rely on beamforming approaches?
> >
> > Thank you for your attention.
> >
> > Best regards,
> >
> > Irene
> >
> > <
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