[FieldTrip] Noise normalization of MNE
rikkert.hindriks at upf.edu
Tue Jun 14 11:44:55 CEST 2016
I'm having trouble interpreting the statistical parametric maps obtained
from MNE source reconstructions using the method described in (Dale, 2000)
. The issue is the following:
For each source location (assume the dipole orientations fixed) the
activity estimate at that location is (approximately) standard normally
the null hypothesis of no activity at all locations.
However, I would like to test for activity at a specific location, but
under the hypothesis
of activity at a specific location, the normalized estimate at
that location is only standard normally distributed if the corresponding
row of the resolution matrix contains a single
In other words: it seems to me that the statistical parametric map can only
be used to test
for activity at individual locations if the source reconstruction is
unbiased (or equivalently:
if the resolution matrix equals the identity matrix) which is not the case
It would be very helpful if someone could help me clarifying this.
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