[FieldTrip] source analysis EEG data without MRI

Ingrid Nieuwenhuis inieuwenhuis at berkeley.edu
Wed Apr 10 01:29:31 CEST 2013


Hi all,

A follow up on this and some new issues:

1) I first tried Jörn's approach by creating my own BEM, always fun to 
make it yourself ;) However, I did not succeed since:
a) the dipoli method does not work on Windows
b) I downloaded the openmeeg toolbox, but got an error "om_minverser.exe 
has stopped working" I've emailed their buglist
c) bemcp did run, but the result was not ok (see attachement). I also 
got the warning "% Warning: Matrix is singular, close to singular or 
badly scaled. Results may be inaccurate." several times, so that might 
be the problem.
d) and asa gave the following error: % Error using ft_prepare_headmodel 
(line 201) % You must supply a valid cfg.hdmfile for use with ASA headmodel

And away went my determination to do it myself, so I continued using 
thestandard_bem.mat 
<http://fieldtrip.fcdonders.nl/template/headmodel?s[]=standard&s[]=bem>. 
(I did not know this existed, I've added this link to note in the 
headmodel tutorial 
<http://fieldtrip.fcdonders.nl/tutorial/headmodel_eeg?&#background> to 
make it easier to find, thanks Tzvetan for pointing this out!).

2) This worked and after some fiddling to get the electrodes aligned it 
looks okay (see attached).
However, as you can see in the figures, I have several very low 
electrodes, that are lower than the skin mesh. So I was wondering if 
this is a problem? Since for accurate calculation of how the currents 
flow from these low electrodes, I assume one needs the skin to go till 
there? What happens when I have electrodes floating in thin air?
*So my question is:*
a) will this cause great inaccuracies?
b) if so, how can I extend the skin to go lower? The template MRI only 
goes that far to the bottom... Trick anyone?

Thanks again,
Ingrid


On 4/9/2013 9:39 AM, Ingrid Nieuwenhuis wrote:
> Thanks Jörn and Tzvetan for the scripts! I'll try it out and put it on 
> the wiki.
> Have a great day,
> Ingrid
>
> On 4/9/2013 12:32 AM, Tzvetan Popov wrote:
>> Dear Ingrid,
>>
>> in addition to Jorn's approach since you don't have MR and digitized 
>> elec position's you can load and realign the electrodes to the 
>> standard bem. Subsequently you can calculate the lead field and 
>>  continue with your analysis pipeline.
>> Good luck
>> tzvetan
>> %% read electrodes
>> elec = ft_read_sens('/your 
>> path/fieldtrip-20130324/template/electrode/GSN-HydroCel-128.sfp');
>> %% read  headmodel
>> templateheadmodel = '/your 
>> path/fieldtrip-20130324/template/headmodel/standard_bem.mat';
>> load(templateheadmodel);
>> %% electrode realign as good as possible
>> % i.e. translate 0 -2 1.5
>> cfg=[];
>> cfg.method = 'interactive';
>> cfg.elec = elec;
>> cfg.headshape = vol.bnd(1).pnt;
>> elecR = ft_electroderealign(cfg);
>> %% verify how the electrodes fit toghether with the brain volume
>> cfg=[];
>> cfg.method = 'interactive';
>> cfg.elec = elecR;
>> cfg.headshape = vol.bnd(3).pnt;
>> elecR = ft_electroderealign(cfg);
>>
>>
>>> Hi Ingrid,
>>>
>>> I just happen to done this a few weeks back, I changed things in the 
>>> meanwhile, but I hope that the below steps are complete:
>>> /% read in the template MRI
>>>     if isunix
>>>       mri = 
>>> ft_read_mri('/home/common/matlab/fieldtrip/external/spm8/templates/T1.nii');
>>>     elseif ispc
>>>       mri = ft_read_mri(fullfile('M:', 'FieldTrip', 'trunk', 
>>> 'external', 'spm8', 'templates', 'T1.nii'));
>>>     end
>>>
>>>
>>> % segment the MRI
>>> cfg           = [];
>>> cfg.output    = {'brain'  'skull'  'scalp'};
>>> segmentedmri  = ft_volumesegment(cfg, mris);
>>>
>>>
>>> % create the headmodel (BEM)
>>> cfg        = [];
>>> %cfg.method ='openmeeg'; % TODO FIXME download openmeeg
>>> if isunix
>>>   cfg.method ='dipoli'; % dipoli only works under linux
>>> else
>>>   disp('TODO FIXME stick to dipoli for now or download openmeeg\n');
>>>   keyboard;
>>> end
>>> hdm        = ft_prepare_headmodel(cfg, segmentedmri);
>>>
>>> elec       = ft_read_sens('standard_1020.elc');
>>> hdm        = ft_convert_units(hdm, elec.unit);
>>>
>>>   cfg = [];
>>>   cfg.grid.xgrid  = -125:8:125;
>>>   cfg.grid.ygrid  = -125:8:125;
>>>   cfg.grid.zgrid  = -125:8:125;
>>>   cfg.grid.tight  = 'yes';
>>>   cfg.grid.unit   = hdm.unit;
>>>   cfg.inwardshift = -1.5;
>>>   cfg.vol        = hdm;
>>>   grid  = ft_prepare_sourcemodel(cfg)
>>>   grid        = ft_convert_units(grid, elec.unit);
>>>
>>> figure;
>>> hold on;
>>> ft_plot_mesh(hdm.bnd(1), 'facecolor',[0.2 0.2 0.2], 'facealpha', 
>>> 0.3, 'edgecolor', [1 1 1], 'edgealpha', 0.05);
>>> ft_plot_mesh(grid.pos(grid.inside, :));
>>>
>>> % this step is not necessary, cause you will see that everything is 
>>> already aligned
>>>   cfg           = [];
>>>   cfg.method    = 'interactive';
>>>   cfg.elec      = elec;
>>>   cfg.headshape = hdm.bnd(1);
>>>   tmp  = ft_electroderealign(cfg);
>>>   elec = tmp; % I had a bug here that I couldn't assign elec directly
>>>
>>> %% verify location of occipital electrodes
>>>
>>> occ_elec = elec;
>>> occ_chan = ft_channelselection({'O*', 'PO*', 'Cz*', 'Fz*'}, elec.label);
>>> occ_idx = match_str(elec.label, occ_chan);
>>> occ_elec.chanpos = occ_elec.chanpos(occ_idx, :);
>>> occ_elec.elecpos = occ_elec.elecpos(occ_idx, :);
>>> occ_elec.label = occ_elec.label(occ_idx, :);
>>> figure;
>>> ft_plot_sens(occ_elec)
>>> hold on;
>>> ft_plot_vol(ft_convert_units(hdm, elec.unit))/
>>>
>>>
>>> Afair, that's all that is needed. Of course you need to adjust 
>>> folder and file names.
>>>
>>> Greetings
>>> Jörn
>>>
>>> On 4/9/2013 2:04 AM, Ingrid Nieuwenhuis wrote:
>>>> Hi all,
>>>>
>>>> I'd like to do source analysis (loreta and or DICS) on my EEG data. 
>>>> I don't have anatomical MRIs and I don't have a measurement of the 
>>>> scalp surface. So I'd like to use a template MRI or a template head 
>>>> model that is located in the FieldTrip template directory. I have 
>>>> EGI (128 channels) data and electrode positions (not subject 
>>>> specific, just the standard file also available in FieldTrip 
>>>> electrode template, GSN-HydroCel-128.sfp), but I'm kind of stuck 
>>>> how to start. I don't see any examples on the FieldTrip page of how 
>>>> to make a headmodel and volume conduction model giving only this 
>>>> limited data. I'd be happy to make it into a example Matlab script 
>>>> on the FieldTrip page after I got it to work. Would someone be able 
>>>> to give me some pointers, or example code?
>>>>
>>>> Thanks a lot!
>>>> Ingrid
>>>>
>>>
>>>
>>> -- 
>>> Jörn M. Horschig
>>> PhD Student
>>> Donders Institute for Brain, Cognition and Behaviour
>>> Centre for Cognitive Neuroimaging
>>> Radboud University Nijmegen
>>> Neuronal Oscillations Group
>>> FieldTrip Development Team
>>>
>>> P.O. Box 9101
>>> NL-6500 HB Nijmegen
>>> The Netherlands
>>>
>>> Contact:
>>> E-Mail:jm.horschig at donders.ru.nl
>>> Tel:    +31-(0)24-36-68493
>>> Web:http://www.ru.nl/donders
>>>
>>> Visiting address:
>>> Trigon, room 2.30
>>> Kapittelweg 29
>>> NL-6525 EN Nijmegen
>>> The Netherlands
>>> _______________________________________________
>>> fieldtrip mailing list
>>> fieldtrip at donders.ru.nl <mailto:fieldtrip at donders.ru.nl>
>>> http://mailman.science.ru.nl/mailman/listinfo/fieldtrip
>>
>> *******************************************
>> Tzvetan Popov
>> Clinical Psychology
>> University of Konstanz
>> Box 23
>> 78457 Konstanz, GERMANY
>> Phone: 0049-7531-883086
>> Fax:      0049-7531-884601
>> Email: tzvetan.popov at uni-konstanz.de 
>> <mailto:tzvetan.popov at uni-konstanz.de>
>> *******************************************
>>
>>
>>
>>
>>
>>
>>
>>
>> _______________________________________________
>> fieldtrip mailing list
>> fieldtrip at donders.ru.nl
>> http://mailman.science.ru.nl/mailman/listinfo/fieldtrip
>
> -- 
> Ingrid Nieuwenhuis PhD
> Postdoctoral Fellow
> Sleep and Neuroimaging Laboratory
> Department of Psychology
> University of California, Berkeley
> California 94720-1650
> Tolman Hall, room 5305
>
>
> _______________________________________________
> fieldtrip mailing list
> fieldtrip at donders.ru.nl
> http://mailman.science.ru.nl/mailman/listinfo/fieldtrip

-- 
Ingrid Nieuwenhuis PhD
Postdoctoral Fellow
Sleep and Neuroimaging Laboratory
Department of Psychology
University of California, Berkeley
California 94720-1650
Tolman Hall, room 5305

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