clusterrandanalysis actvsblT

Andre Bastos abastos at BERKELEY.EDU
Tue Jul 31 02:44:10 CEST 2007


Eric,

Yes, I understand about the pvalues not working for comparing within a trial
(from baseline to activation). But what about comparing across different
periods of time, using independent samples? Is it okay to set avgovertime =
'yes' then? 

For example, I am comparing two conditions in a ssvep paradigm: attend left
and attend right, for one subject. I am not quite sure what I am doing
wrong, as I am sure that there are differences between these two conditions,
although the clusters that I get are all insignificant. 

In this case, when the subject attends left they attend to 7.5 Hz, and when
they attend right they attend to 10 Hz flicker stimulus. I am expecting that
these frequencies, as well as higher harmonics will be sensitive to
attention (as previously reported in the ssvep lit). However, my clusters
all have p values above 0.2. I tried this with avgovertime set to both yes
and no, and still no sig clusters. 

Why are the insignificant clusters even returned at all, especially when
there is a parameter value for determining significant clusters,
alphathresh, which is set in the cfg but never used? I know that other
people have had the same issue before...

Thanks again,

Andre

Here is my config (I am using just the 29 parietal and occipital electrodes
for this analysis).

  elec.pnt  = elec.pnt(1:29,:);
  elec.label = elec.label(1:29,:);
  
  cfg=[];
  cfg.statistic = 'indepsamplesT';
  cfg.alphathresh = 0.05;
  cfg.makeclusters = 'yes';
  cfg.minnbchan = 2;
  cfg.clusterteststat = 'maxsum';
  cfg.onetwo = 'twosided';
  cfg.alpha = 0.05;
  cfg.nranddraws = 500;
  cfg.channel = 'all'; %TFR(1).elec.label(1:64); %{'EEG'};
  cfg.latency = [1 5 ];
  cfg.elec = elec;
  cfg.neighbourdist    = 49;
  cfg.avgovertime = 'no';
  
  [clusrand] = clusterrandanalysis(cfg, TFR1, TFR2);


-----Original Message-----
From: FieldTrip discussion list [mailto:FIELDTRIP at NIC.SURFNET.NL] On Behalf
Of Eric Maris
Sent: Monday, July 30, 2007 3:42 PM
To: FIELDTRIP at NIC.SURFNET.NL
Subject: Re: [FIELDTRIP] clusterrandanalysis actvsblT

Dear Andre,

> On a related note, I would like to ask about the clusterrandanalysis
option
> to set avgovertime = 'yes'
> 
> In this case, as far as I am aware, the frequency-space-time-trial
quadlets
> which clusterrand analysis uses become doublets of frequency-space. In
this
> case, wouldn't it be possible to compare data periods of different
lengths,
> as clusterrandanalysis would just average across your baseline period as
set
> 1 and average across the activation period as set 2?
> 
> Does the distribution of activation over time get factored in to the
> clusterrandanalysis function even when avgovertime is set to 'yes'?


If you try to do this, you should get an error message. Have a try, and if
you don't get an error message let me know. Anyhow, even without an error
message, the p-value that you get out of clusterrandanalysis only makes
sense if the baseline and activation periods are of equal length.


Good luck,

Eric Maris

 

dr. Eric Maris

NICI/Biological Psychology and

F.C. Donders Center for Cognitive NeuroImaging

University of Nijmegen

P.O. Box 9104

6500 HE Nijmegen

The Netherlands

T:+31 24 3612651 (NICI)

T:+31 24 3610754 (FCDC)

F:+31 24 3616066 (NICI)

E: maris at nici.ru.nl

MSc Cognitive Neuroscience :www.ru.nl/master/cns/







> 
> Thanks,
> 
> -Andre
> 
> 
> -----Original Message-----
> From: FieldTrip discussion list [mailto:FIELDTRIP at NIC.SURFNET.NL] On
Behalf
> Of Eric Maris
> Sent: Monday, July 30, 2007 1:50 PM
> To: FIELDTRIP at NIC.SURFNET.NL
> Subject: Re: [FIELDTRIP] clusterrandanalysis actvsblT
> 
> Dear Claudia,
> 
> 
> 
> > i have a questions about clusteranalysis comparing baseline and
> > activation period. is it really impossible to compare two periods of
> > different length? and why? as far as i understand the mean of the
> > baseline is used and so you have only one value per frequency anyway.
> > can i avoid this problem or do i have to divide my activation period
> > into different segments because my baseline period is much shorter?
> 
> 
> You are one of many to complain about this feature of clusterrandanalysis.
> Nevertheless, you do have to divide your activation period into different
> segments. The reason for this has to do with the null hypothesis that is
> tested when you use the activation-versus-baseline statistic. This null
> hypothesis is the following: The data in the baseline period are drawn
from
> the same probability distribution (over the spatiotemporal domain) as the
> data in the activation period. This null hypothesis only makes sense if
the
> spatiotemporal dimensionality of the activation and the baseline period
are
> equal.
> 
> 
> Kind regards,
> 
> Eric Maris
> 
> 
> 
> 
> 
> 
> 
> 
> dr. Eric Maris
> 
> NICI/Biological Psychology and
> 
> F.C. Donders Center for Cognitive NeuroImaging
> 
> University of Nijmegen
> 
> P.O. Box 9104
> 
> 6500 HE Nijmegen
> 
> The Netherlands
> 
> T:+31 24 3612651 (NICI)
> 
> T:+31 24 3610754 (FCDC)
> 
> F:+31 24 3616066 (NICI)
> 
> E: maris at nici.ru.nl
> 
> MSc Cognitive Neuroscience :www.ru.nl/master/cns/
> 
> 
> 
> 
> > thanks in advance
> > claudia
> >
> >
> > --
> > Pflichtangaben gemäß Gesetz über elektronische Handelsregister und
> > Genossenschaftsregister sowie das Unternehmensregister (EHUG):
> >
> > Universitätsklinikum Hamburg-Eppendorf
> > Körperschaft des öffentlichen Rechts
> > Gerichtsstand: Hamburg
> >
> > Vorstandsmitglieder:
> > Prof. Dr. Jörg F. Debatin (Vorsitzender)
> > Dr. Alexander Kirstein
> > Ricarda Klein
> > Prof. Dr. Dr. Uwe Koch-Gromus
> 
> ----------------------------------
> The aim of this list is to facilitate the discussion between users of the
> FieldTrip  toolbox, to share experiences and to discuss new ideas for MEG
> and EEG analysis. See also
> http://listserv.surfnet.nl/archives/fieldtrip.html and
> http://www.ru.nl/fcdonders/fieldtrip.
> 
> ----------------------------------
> The aim of this list is to facilitate the discussion between users of the
FieldTrip
> toolbox, to share experiences and to discuss new ideas for MEG and EEG
analysis.
> See also http://listserv.surfnet.nl/archives/fieldtrip.html and
> http://www.ru.nl/fcdonders/fieldtrip.

----------------------------------
The aim of this list is to facilitate the discussion between users of the
FieldTrip  toolbox, to share experiences and to discuss new ideas for MEG
and EEG analysis. See also
http://listserv.surfnet.nl/archives/fieldtrip.html and
http://www.ru.nl/fcdonders/fieldtrip.

----------------------------------
The aim of this list is to facilitate the discussion between users of the FieldTrip  toolbox, to share experiences and to discuss new ideas for MEG and EEG analysis. See also http://listserv.surfnet.nl/archives/fieldtrip.html and http://www.ru.nl/fcdonders/fieldtrip.



More information about the fieldtrip mailing list