<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
</head>
<body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">
<font size="4" class="">Hi Nadia,</font>
<div class=""><font size="4" class=""><br class="">
</font></div>
<div class=""><font size="4" class="">In general, but other may chime in here, I would say that the numbers themselves are not the biggest issue here. What you should ensure is that both groups are as equal as possible w.r.t. all kinds of demographic etc. parameters,
such as age, education level, handedness etc. If this is not balanced to begin with, I wouldn’t be worried about a disbalance in numbers.</font></div>
<div class=""><font size="4" class=""><br class="">
</font></div>
<div class=""><font size="4" class="">Best wishes,</font></div>
<div class=""><font size="4" class=""><br class="">
</font></div>
<div class=""><font size="4" class="">Jan-Mathijs</font></div>
<div class=""><font size="4" class=""><br class="">
</font></div>
<div class=""><font size="4" class=""><br class="">
</font>
<div><br class="">
<blockquote type="cite" class="">
<div class="">On 22 Sep 2020, at 23:01, Nadia Youssef <<a href="mailto:nadiayoussef635@yahoo.com" class="">nadiayoussef635@yahoo.com</a>> wrote:</div>
<br class="Apple-interchange-newline">
<div class="">
<div class="">
<div class="yahoo-style-wrap" style="font-family:Helvetica Neue, Helvetica, Arial, sans-serif;font-size:16px;">
<div dir="ltr" data-setdir="false" class="">
<div class="">
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
Hi everyone, </div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
<br class="">
</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
In my dataset, I have an unequal number of Normal and MCI (MCI=30, Normal=50).</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
In which, this unbalanced sample size will affect the analysis (Brain network analysis) and any idea on how to solve this issue?</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
<br class="">
</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
<br class="">
</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
<br class="">
</div>
<div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;" class="">
Best regards,</div>
</div>
<br class="">
</div>
</div>
</div>
_______________________________________________<br class="">
fieldtrip mailing list<br class="">
<a href="https://mailman.science.ru.nl/mailman/listinfo/fieldtrip" class="">https://mailman.science.ru.nl/mailman/listinfo/fieldtrip</a><br class="">
https://doi.org/10.1371/journal.pcbi.1002202<br class="">
</div>
</blockquote>
</div>
<br class="">
</div>
</body>
</html>