<html><head></head><body><div class="yahoo-style-wrap" style="font-family:Helvetica Neue, Helvetica, Arial, sans-serif;font-size:16px;"><div dir="ltr" data-setdir="false"><div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;">Hi everyone, </div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;"><br></div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;">In my dataset, I have an unequal number of Normal and MCI (MCI=30, Normal=50).</div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;">In which, this unbalanced sample size will affect the analysis (Brain network analysis) and any idea on how to solve this issue?</div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;"><br></div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;"><br></div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;"><br></div><div dir="ltr" style="font-size: 16px; font-family: Helvetica, Arial, sans-serif;">Best regards,</div></div><br></div></div></body></html>