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</o:shapelayout></xml><![endif]--></head><body lang=NL link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span lang=EN-US>Dear FieldTrippers,<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US>For sourceconstruction (CTF275 MEG data) at specific ROIs, I want to compute leadfields at specific (MNI-)coordinates in the brain. I am trying to find out how that is most easily done using FieldTrip<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US>- The most intuitive way seems to me to warp the MNI template to the individual’s brain (<a href="http://fieldtrip.fcdonders.nl/example/create_single-subject_grids_in_individual_head_space_that_are_all_aligned_in_mni_space">http://fieldtrip.fcdonders.nl/example/create_single-subject_grids_in_individual_head_space_that_are_all_aligned_in_mni_space</a>) , and then apply the warping parameters to the ROI’s MNI-coordinates, and enter the subsequent CTF-coordinates into ft_prepare_leadfield. However, I am not sure where exactly I can find these parameters, and how to apply them. Are these the ones in [gridsrc].params (output ft_sourcemodel)?<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US>- Alternatively, should I run ft_volumenormalise to warp the brain to MNI-space, and then inversely apply the warping parameters to the ROI’s MNI-coordinates? Again, where can I find the warping parameters in this case, and how should they be applied?<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US>Best,<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US>Stan<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.0pt;font-family:"Times New Roman","serif"'>-<br>Stan van Pelt, PhD<br>Donders Institute for Brain, Cognition and Behaviour<br>Centre for Cognition<br>Montessorilaan 3, B.01.34<br>6525 HR Nijmegen, the Netherlands<br>tel: +31 24 3616288</span><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span lang=EN-US><o:p></o:p></span></p></div></body></html>