<div dir="ltr"><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">Hi all,</span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr">
<span style="font-family:Arial,sans-serif">We have a question regarding normalisation of EEG signals for source reconstruction analysis.</span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr">
<span style="font-family:Arial,sans-serif;font-size:11pt;line-height:15.555556297302246px">We have EEG records (not ERP) of a few patients in two different conditions (each condition consists of several 2 seconds segments/trials). Each recording was done over a period of a few days, and in different sessions. We also have anatomycal MRI scans for each patient (subject).</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">We would like to make two statistic comparisons:</span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin:0cm 0cm 0.0001pt 18pt;direction:ltr">
<span style="font-family:Arial,sans-serif">1.<span style="font-size:7pt;font-family:'Times New Roman'">    </span></span><span dir="LTR"></span><span style="font-family:Arial,sans-serif">Compare the source analysis of the two conditions in each subject.</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin:0cm 0cm 0.0001pt 18pt;direction:ltr"><span style="font-family:Arial,sans-serif">2.<span style="font-size:7pt;font-family:'Times New Roman'">    </span></span><span dir="LTR"></span><span style="font-family:Arial,sans-serif">Compare the source analysis of the two conditions, based upon all subjects.</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">For the first comparison, we are puzzled about the appropriate way to normalise and standardize our data, since each EEG segment was recorded at a different time, and hence may be affected by different electrode conductivity, for example. How would you normalise the data?</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">For the second comparison, of course, we would like to normalise the source analysis results in the anatomycal level using ft_volumenormalise.</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">However, we are puzzled about the appropriate way to normalise and standardize our data, since subjects differ from each other (for example, anatomycally, resulting in changes of power spectrum).</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">How would you standartize the data between subjects?</span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr">
<span style="font-family:Arial,sans-serif"> </span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">Thank you very much,</span></p>
<p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr"><span style="font-family:Arial,sans-serif">best regards,</span></p><p style="font-family:arial,sans-serif;font-size:13.333333969116211px;margin-bottom:0.0001pt;direction:ltr">
<span style="font-family:Arial,sans-serif">Aia and Roey</span></p></div>