<html><head></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; color: rgb(0, 0, 0); font-size: 14px; font-family: Calibri, sans-serif; "><div><b><i>Postdoctoral Position Available et the Montreal Neurological Institute</i></b></div><span id="OLK_SRC_BODY_SECTION"><div style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; color: rgb(0, 0, 0); font-size: 14px; font-family: Calibri, sans-serif; "><span id="OLK_SRC_BODY_SECTION"><div style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; color: rgb(0, 0, 0); font-size: 14px; font-family: Calibri, sans-serif; "><p style="margin: 0px; "><b><i><br></i></b></p><p style="margin: 0px; "><b><i>Multimodal Functional Imaging Laboratory, Biomedical Engineering Dpt,</i></b></p><p style="margin: 0px; "><b><i>Montreal Neurological Institute, McGill University, Montreal, Canada</i></b></p><p style="margin: 0px; "><br></p><p style="margin: 0px; ">The candidate will join a multidisciplinary team composed of neurologists and methodologists</p><p style="margin: 0px; ">within the Multimodal Functional Imaging Laboratory and in close collaboration with the epilepsy</p><p style="margin: 0px; ">group of the Montreal Neurological Institute. A brief description of the project can be found below.</p><p style="margin: 0px; ">The main role of the candidate will be to recruit patients, to assist data acquisition and to identify</p><p style="margin: 0px; ">epileptic events on recorded signals. (S)he will be trained to contribute to data acquisition and to</p><p style="margin: 0px; ">use dedicated source localization and data fusion techniques developed locally. Initial appointment</p><p style="margin: 0px; ">is for 1 year, with possibility of renewal up to 3 years.</p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><b><i>Project: Multimodal investigation of epileptic activity using simultaneous</i></b></p><p style="margin: 0px; "><b><i>EEG/MEG and EEG/NIRS acquisitions.</i></b></p><p style="margin: 0px; "><br></p><p style="margin: 0px; ">The proposed project aims at localizing and characterizing the generators of epileptic activity using</p><p style="margin: 0px; ">simultaneous acquisitions of ElectroEncephaloGraphy (EEG) with Magneto-EncephaloGraphy</p><p style="margin: 0px; ">(MEG), as well as simultaneous acquisitions of EEG with Near Infra-Red Spectroscopy (NIRS).</p><p style="margin: 0px; ">ElectroEncephaloGraphy (EEG) and Magneto-EncephaloGraphy (MEG) are respectively measuring on the</p><p style="margin: 0px; ">scalp electric and magnetic fields generated by neuronal activity at a millisecond scale, providing a detailed</p><p style="margin: 0px; ">description of brain activity using 275 MEG sensors and 56 EEG electrodes. Combined with EEG measuring</p><p style="margin: 0px; ">brain electric activity on the scalp, NIRS allows studying hemodynamic processes at the time of spontaneous</p><p style="margin: 0px; ">epileptic activity. The specificity of NIRS data is its ability to measure local changes oxy-hemoglobin (HbO)</p><p style="margin: 0px; ">and deoxy-hemoglobin (HbR), exploiting absorption properties of infrared light within brain tissue using</p><p style="margin: 0px; ">optic fibers placed on the surface of the head (temporal resolution: 10 ms, 16 sources x 32 detectors,</p><p style="margin: 0px; ">penetration: 2-3 cm from the surface of the head). The candidate will be trained to use the first Brainsight</p><p style="margin: 0px; ">NIRS device developped by Rogue-Research Inc, with which we were able to record promising preliminary</p><p style="margin: 0px; ">data.</p><p style="margin: 0px; ">While methodological developpments in the lab will consist in 3D reconstruction of the generators of</p><p style="margin: 0px; ">EEG, MEG and NIRS signals and assessing multimodal concordances between bioelectrical neuronal signals</p><p style="margin: 0px; ">and hemodynamic processes, the purpose of this Postdoctoral project will be to assess the integrity of</p><p style="margin: 0px; ">neurovascular coupling processes at the time of epileptic discharges, using a unique multimodal</p><p style="margin: 0px; ">environment involving EEG/MEG, EEG/NIRS and also EEG/fMRI recordings. Close collaborations with the</p><p style="margin: 0px; ">epilepsy group of the Montreal Neurological Institute, involving notably Dr E. Kobayashi MD-PhD, Dr F.</p><p style="margin: 0px; ">Dubeau MD-PhD and Dr. J. Gotman PhD, will provide access to patient populations and additional clinical</p><p style="margin: 0px; ">expertise for this project.</p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><b><i>Requirements: </i></b>The candidate should be an MD (neurologist) with previous training in epileptology and</p><p style="margin: 0px; ">neurophysiology (EEG). Expertise in analyzing MEG or NIRS signals and/or computational skills including</p><p style="margin: 0px; ">neuroimaging softwares are appreciated additional qualification. The candidate should be fluent in English</p><p style="margin: 0px; ">(and if possible French) due to the patient population studied.</p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><br></p><p style="margin: 0px; "></p><p style="margin: 0px; ">Supervisor: Christophe Grova Ph.D.</p><p style="margin: 0px; ">Assistant Professor, Biomedical Engineering</p><p style="margin: 0px; ">Assistant Professor, Neurology & Neurosurgery</p><p style="margin: 0px; ">Director of the Multimodal Functional Imaging Laboratory</p><p style="margin: 0px; color: rgb(4, 51, 255); "><span style="color: rgb(0, 0, 0); ">Email: </span><a href="mailto:christophe.grova@mcgill.ca">christophe.grova@mcgill.ca</a></p><p style="margin: 0px; color: rgb(4, 51, 255); "><span style="color: rgb(0, 0, 0); ">Multi FunkIm Lab: </span><a href="http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/HomePage">http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/HomePage</a></p><p></p><p style="margin: 0px; "><br></p><p style="margin: 0px; ">Please send your CV, a motivation letter and reference letters to <span style="color: rgb(4, 51, 255); "><a href="mailto:christophe.grova@mcgill.ca">christophe.grova@mcgill.ca</a></span></p><p style="margin: 0px; "><span style="color: #0433ff"><br></span></p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><br></p><p style="margin: 0px; "><span style="font-family: Tahoma; font-size: 10pt; ">***************************<br>Christophe Grova, PhD<br>Assistant Professor<br>Biomedical Engineering Dpt<br>Neurology and Neurosurgery Dpt<br><br><font size="2">Multi<font size="2">modal Funct<font size="2">ional Imaging Lab (Multi FunkIm) </font></font></font><br>Montreal Neurological Institute<br>Centre de Recherches en Mathématiques<br><br>Biomedical Engineering Department - Room 304 McGill University<br>3775 University Street, Montreal, Quebec, Canada, H3A 2B4 <br>email : <a href="mailto:christophe.grova@mcgill.ca">christophe.grova@mcgill.ca</a> <br>tel : (514) 398 2516 <br>fax : (514) 398 7461<br><br>web:<br><font size="2"><a href="http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/PeopleChristophe">http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/PeopleChristophe</a><br></font></span><font size="2" style="font-family: Tahoma; font-size: small; "><span style="font-size: 10pt; "><font size="2"><span style="font-size: 10pt; "><font size="2"><span style="font-size: 10pt; "><a href="https://exchange.mcgill.ca/owa/redir.aspx?C=b3c34a70f6004b0db2031104a06b167e&URL=http%3a%2f%2fwww.bmed.mcgill.ca%2f" target="_blank">http://www.bmed.mcgill.ca/</a><br></span></font></span></font>MultiFunkIm Lab: <br><a href="http://www.bic.mni.mcgill.ca/ResearchLabsMFI">http://www.bic.mni.mcgill.ca/ResearchLabsMFI</a><font size="2">L</font>/HomePage<br></span></font><font size="2" style="font-family: Tahoma; font-size: small; "><span style="font-size: 10pt; "><br>***************************</span></font></p><p style="font-size: 12px; font-family: Helvetica; margin: 0px; "><br></p></div></span></div></span></body></html>