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<p class="MsoNormal"><span lang="EN-GB">Dear Fieldtrippers, <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">if I do ICA in my preprocessing to reject EOG and ECG signals, the new MEG guidelines say that this might alter later source reconstruction and connectivity analyses (which I aim to do).<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">So, worried about this, I wonder if applying ft_rejectcomponent on my raw dataset
<o:p></o:p></span></p>
<p class="MsoListParagraph" style="text-indent:-18.0pt;mso-list:l0 level1 lfo1"><![if !supportLists]><span lang="EN-GB"><span style="mso-list:Ignore">1.)<span style="font:7.0pt "Times New Roman"">   
</span></span></span><![endif]><span lang="EN-GB">automatically modifies the leadfield matrix?<o:p></o:p></span></p>
<p class="MsoListParagraph" style="text-indent:-18.0pt;mso-list:l0 level1 lfo1"><![if !supportLists]><span lang="EN-GB"><span style="mso-list:Ignore">2.)<span style="font:7.0pt "Times New Roman"">   
</span></span></span><![endif]><span lang="EN-GB">the unmixing (and mixing?) matrix is saved in the new data structure somewhere (to evtl make use of it at later analysis steps)?<o:p></o:p></span></p>
<p class="MsoListParagraph" style="text-indent:-18.0pt;mso-list:l0 level1 lfo1"><![if !supportLists]><span lang="EN-GB"><span style="mso-list:Ignore">3.)<span style="font:7.0pt "Times New Roman"">   
</span></span></span><![endif]><span lang="EN-GB">automatically stores the information how many and what ICA components were subtracted from the data in my new data structure.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">Would you generally discourage to apply ICA in the preprocessing when planning source reconstruction and connectivity analysis?<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">It’s a complicated topic for me as a clinician so I hope there is no mixing in my questions ;-)<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">Many thanks for your answers, <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB">Patrick<o:p></o:p></span></p>
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