<div>Dear Paul and Carsten,</div>
<div>The conductivity ratio of 1/20 that you mention is indeed on the low side of</div>
<div>many present estimates. It is way lower than the Rush & Driscoll 1/80 </div>
<div>ratio that we used in our 30 year old "Ary Correction" paper that examined </div>
<div>the effect of skull and scalp thickness. My big worry however is</div>
<div>not simply to find the ratio (taking individual differences into account). but</div>
<div>also to get estimates of the differences in conductivity across the skull.</div>
<div>I'm pretty confident that such inhomogeneities are present and that they will </div>
<div>have significant effects on the BEM forward models. The inhomogeneities</div>
<div>will not only affect the effective depth of sources but also can laterally shift</div>
<div>their locations to places on cortex with very different surface normals.</div>
<div> </div>
<div>An important aspect of our EEG/MEG source localization work is to learn </div>
<div>how to calibrate each individual's conductivity partly based on differences </div>
<div>in EEG vs MEG localizations. </div>
<div> </div>
<div>best,</div>
<div>Stan</div>
<div><br><br> </div>
<div class="gmail_quote">On Mon, Oct 25, 2010 at 4:40 AM, Paul Czienskowski <span dir="ltr"><<a href="mailto:paul_c@gmx.de">paul_c@gmx.de</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="PADDING-LEFT: 1ex; MARGIN: 0px 0px 0px 0.8ex; BORDER-LEFT: #ccc 1px solid">
<div bgcolor="#ffffff" text="#000000">Dear all,<br><br>Alexandre Gramford pointed out to me that there was some discussion ongoing on which conductivities to use for EEG-Forward-Modeling and I'd like to move this discussion more to public for it could be interesting for many of us. <br>
I was recently overflying some papers concerned with that very issues and I made some interesting and discoveries, especially in <br>
<blockquote>Conductivity of living intracranial tissues. by Latikka J, Kuurne T, Eskola H.<br>The electrical conductivity of human cerebrospinal fluid at body temperature by Baumann et al.<br></blockquote>The first one measured the conductivities (or resistivities) of living brain tissue and came to values of 3.51 Ohms*m and 3.91 Ohms*m for grey respectively white matter and 0.80 Ohms*m for the CSF (which are about 0.28, 0.256 and 1.25 S/m). In contrary the second one found a value for 1.79 S/m for CSF at body temperature where it was about 1.4 S/m at room temperature. The Skull-To-Brain conductivity ratio was measured for example in<br>
<blockquote>Estimation of <em>in vivo</em> brain-to-skull conductivity ratio in humans by Yingchun Zhang, Wim van Drongelen, and Bin He<br></blockquote>where they found a ratio of about 1/18.7 which is way larger than the commonly assumed value.<br>
<br>I would appreciate very much if many of you could contribute to this discussion by telling us which values you use for the conductivities and on which publications the are based.<br><br>Best,<br>Paul<br><pre cols="72">
--
Paul Czienskowski
Max Planck institute for human development
Lentzeallee 94
14195 Berlin
Björnsonstr. 25
12163 Berlin
Tel.: (+49)(0)30/221609359
Handy: (+49)(0)1788378772</pre></div>
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